Review warns of lean mass and vitamin deficits on GLP-1 therapy

The wire

1. 01A narrative review examines how semaglutide, tirzepatide and newer satiety hormone agonists alter hunger, satiety, satiation and reward eating.
2. 02Author notes loss of lean tissue including bone and muscle plus reported vitamin deficiencies, arguing nutritional counseling and possible dose adjustment are central to care.
3. 03It is a narrative review without pooled estimates, so the frequency and magnitude of deficiencies remain unquantified.

From the source

Effect of GLP-1 receptor agonist on nutrient intake: A narrative review

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026 Sep 17 · Fujioka K et al.