UC San Diego team reports catestatin cuts tau and amyloid in mice
The naturally occurring chromogranin A fragment also reduced brain inflammation and improved cognitive and motor function in mouse models, researchers say.
PR
By Priya Raman · Science Reporter
Sep 23 07:44 ETSource: Technology Networks
The wire
- 01Researchers at UC San Diego School of Medicine report that catestatin, a peptide derived from chromogranin A, reduced tau and amyloid accumulation and neuroinflammation in mouse models of neurodegeneration.
- 02Senior author Sushil K. Mahata says the peptide acts across several disease pathways at once, a contrast with single-target approaches in Alzheimer's drug development.
- 03Work remains in mice; the team says it is still investigating whether catestatin changes how the brain produces and uses energy, and no human data exist.
From the source
Read at technologynetworks.comOne Small Peptide Could Tackle Multiple Neurodegenerative Diseases
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