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Researchprogeriahmga1agingnature communications

Nature paper ties HMGA1-HP1β axis to progeria aging

Chromatin remodeling mechanism may explain premature aging in Hutchinson-Gilford progeria syndrome, researchers report.

PR
By Priya Raman · Science Reporter
Aug 18 20:00 ETSource: Nature communications

The wire

  1. 01Researchers describe an HMGA1-HP1β axis regulating premature aging via chromatin remodeling.
  2. 02The mechanism offers a potential target in a rare accelerated-aging disease.
  3. 03Findings are laboratory-stage with no therapy identified.

From the source

HMGA1-HP1β axis regulates premature aging in Hutchinson-Gilford progeria syndrome through chromatin remodeling

Nature communications · 2026 Aug 19 · Hu Q, Sun Q, Xiang W et al.

Read at pubmed.ncbi.nlm.nih.gov
Source URL https://pubmed.ncbi.nlm.nih.gov/42749700/