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Chart review finds 2.39% HbA1c drop on weekly GLP-1s in African American patients

Ninety-one patients on dulaglutide or semaglutide for at least 26 weeks also lost a mean 4.76 kg at an adult medicine clinic.

PR
By Priya Raman · Science Reporter

The wire

  1. 01In a retrospective chart review of 91 patients, 85.7% African American, mean age 56.4, HbA1c fell 2.39% and weight fell 4.76 kg over a mean 14.9 months of treatment (both p<.001).
  2. 02African Americans are underrepresented in real-world GLP-1 data, so the results give clinicians a reference point for outcomes in this population.
  3. 03The study is retrospective, single-clinic and uncontrolled; high-dose dulaglutide outperformed low-dose (p=.023), but drivers of differential response remain unexamined.

From the source

Real-World Impact of Weekly Dulaglutide and Semaglutide on Hba1c and Weight in a Predominantly Underrepresented Demographic

Journal of health care for the poor and underserved · 2026 · Deas C, Uhomba L, Snow K et al.

Read at pubmed.ncbi.nlm.nih.gov