Thursday, September 17, 2026RSS
Peptide.Wire

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Researchgbp2pancreatic canceroncology

GBP2 drives pancreatic cancer proliferation via SP1/SKP2/P27 axis

Journal of Translational Medicine study identifies a cell-cycle pathway promoting tumor growth in pancreatic cancer.

PR
By Priya Raman · Science Reporter
Aug 16 20:00 ETSource: Journal of translational medicine

The wire

  1. 01Researchers report GBP2 promotes pancreatic cancer proliferation through SP1/SKP2/P27 signaling.
  2. 02The axis could represent a therapeutic target in a hard-to-treat cancer.
  3. 03No drug candidate or clinical testing was reported.

From the source

Guanylate-binding protein 2 (GBP2) drives pancreatic cancer cell proliferation by promoting cell cycle progression via the SP1/SKP2/P27 axis

Journal of translational medicine · 2026 Aug 17 · Fang S, Nie H, Zhou J et al.

Read at pubmed.ncbi.nlm.nih.gov
Source URL https://pubmed.ncbi.nlm.nih.gov/42750038/