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Lancet publishes randomised trial of weekly semaglutide in alcohol use disorder

The double-blind, placebo-controlled study enrolled patients with alcohol use disorder and comorbid obesity, a population where incretin effects on drinking have been debated.

PR
By Priya Raman · Science Reporter
May 2 03:00 ETSource: The Lancet

The wire

  1. 01The Lancet reports a randomised, double-blind, placebo-controlled trial of once-weekly semaglutide versus placebo in patients with alcohol use disorder and comorbid obesity.
  2. 02Off-label interest in GLP-1s for addiction has run ahead of controlled data, so a randomised readout gives clinicians something firmer to cite.
  3. 03Results should be read against the enrolled population, which had comorbid obesity, limiting generalisation to patients with alcohol use disorder alone.

From the source

Once-weekly semaglutide versus placebo in patients with alcohol use disorder and comorbid obesity: a randomised, double-blind, placebo-controlled trial

Read at thelancet.com