Study maps metal coordination and antimicrobial activity of LL-37 analogues

The wire

1. 01Researchers characterized coordination chemistry and antimicrobial activity across LL-37, a C-terminal fragment and a peptidomimetic analogue.
2. 02Metal binding may influence how host-defense peptides kill bacteria and guide analogue design.
3. 03No in vivo or clinical testing reported.

From the source

Coordination chemistry and antimicrobial activity of LL-37, its C-terminal fragment, and a peptidomimetic analogue

Dalton transactions (Cambridge, England : 2003) · 2026 Sep 8 · Szarszoń K, Luszawska M, Jewgiński M et al.