Lancet publishes phase 3 retatrutide data in type 2 diabetes
TRANSCEND-T2D-1 tested the triple GIP, GLP-1 and glucagon receptor agonist in patients inadequately controlled on diet and exercise.
MH
By Maren Holt · Senior Reporter, GLP-1
Jun 6 03:00 ETSource: The Lancet
The wire
- 01The double-blind, randomised phase 3 trial evaluated retatrutide for efficacy and safety in people with type 2 diabetes not controlled by diet and exercise alone.
- 02Retatrutide is the most closely watched triple agonist in the incretin pipeline, and drug-naive diabetes data inform its eventual label scope.
- 03Effect sizes, dosing arms and tolerability details are in the full publication; regulatory filings and timing were not addressed.
From the source
Read at thelancet.comEfficacy and safety of retatrutide, a GIP, GLP-1, and glucagon receptor agonist, in people with type 2 diabetes and inadequate glycaemic control with diet and exercise (TRANSCEND-T2D-1): a double-blind, randomised, phase 3 trial