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Photoswitchable peptide drives luteinizing hormone release in female mice

Researchers optically controlled hypothalamic arcuate kisspeptin neurons, triggering LH secretion, in a Journal of Neuroendocrinology report.

PR
By Priya Raman · Science Reporter
Aug 31 20:00 ETSource: Journal of neuroendocrinology

The wire

  1. 01A light-controlled peptide was used to manipulate arcuate nucleus kisspeptin neurons in female mice.
  2. 02Demonstrates precise optical tools for probing reproductive neuroendocrine circuits.
  3. 03Therapeutic application of photoswitchable peptides is not addressed.

From the source

Optical control of the hypothalamic arcuate nucleus kisspeptin neuronal network with a photoswitchable peptide that drives luteinizing hormone release in female mice

Journal of neuroendocrinology · 2026 Sep · Qiu J, Lin Y, Bartram E et al.

Read at pubmed.ncbi.nlm.nih.gov
Source URL https://pubmed.ncbi.nlm.nih.gov/42711067/