GLP-1semaglutidetirzepatideobesitykidney transplant

GLP-1 plus group coaching yields 3.4% weight loss in transplant candidates

Attendance at the 15-week virtual curriculum, not drug use alone, tracked with weight loss in the single-arm COMPKT feasibility study.

By Maren Holt · Senior Reporter, GLP-1

Sep 25 20:00 ETSource: The science of diabetes self-management and care

The wire

01In 29 kidney transplant candidates with median BMI 41.1 kg/m2, GLP-1 or GLP-1/GIP use rose from 62.1% to 72.4% over 15 weekly virtual sessions; median weight change was -3.44%.
02Transplant programs excluding candidates above BMI 35 now have a feasibility signal for combining interprofessional pharmacotherapy management with structured lifestyle coaching; two participants were transplanted during the evaluation.
03Single-arm academic-center study with 29 analyzed participants and poor attendance in nearly half the cohort; authors report engagement rather than GLP-1 therapy alone appeared to drive outcomes.

From the source

Feasibility of the Comprehensive Overweight/Obesity Management Pre-Kidney Transplant Program: A Group-Based Lifestyle Intervention and GLP-1 Receptor Agonist Therapy for End-Stage Kidney Disease Candidates Ineligible Due to Obesity
The science of diabetes self-management and care · 2026 Sep 26 · Sisson EM, Burns D, Wheeler SE et al.

Read at pubmed.ncbi.nlm.nih.gov

Source URL https://pubmed.ncbi.nlm.nih.gov/42800900/