Friday, September 18, 2026RSS
Peptide.Wire

The daily wire on therapeutic peptides. Regulatory, research, compounding and the incretin race, condensed.

Regulatorycagrisemanovo nordisksemaglutidecagrilintidelitigation

US judge lets CagriSema investor fraud claims against Novo Nordisk proceed

Judge Robert Kirsch kept the REDEFINE-1 flexible-dosing allegations alive but dismissed claims that Novo's 25% weight-loss expectation was misleading, calling it aspirational.

DO
By Daniel Okafor · Regulatory Correspondent
Jul 29 03:00 ETSource: pharmaphorum

The wire

  1. 01The class action covers investors who bought Novo Nordisk stock between November 2022 and December 2024, when REDEFINE-1 showed 20.4% weight loss at 68 weeks and shares fell nearly 18%.
  2. 02Central claim: then-development head Martin Holst Lange allegedly concealed that flexible dosing let patients adjust CagriSema, with only 57% reaching the top dose, implying a tolerability issue.
  3. 03Novo filed CagriSema for obesity in the US last December with a decision due in coming months, after REDEFINE-4 showed it less effective than Lilly's Zepbound.

From the source

US judge says Novo Nordisk must face lawsuit over CagriSema

A US judge has ordered that Novo Nordisk must face some allegations in court that it defrauded investors by making misleading comments about a trial of its obesity drug CagriSema.

Read at pharmaphorum.com