Trialssemaglutidemetforminpcosobesity

Bangladesh trial completes low-dose semaglutide plus metformin test in obese PCOS

The open-label Phase 2/3 study randomized 30 women to semaglutide 0.5 mg weekly with metformin or metformin alone over 12 weeks.

By Priya Raman · Science Reporter

Oct 7 08:00 ETSource: ClinicalTrials.gov

The wire

01NCT06896981, sponsored by Bangabandhu Sheikh Mujib Medical University in Dhaka, is listed as completed; it compared low-dose semaglutide (0.25 mg weekly for 4 weeks, then 0.5 mg weekly) plus metformin 500 mg twice daily against metformin alone.
02Clinicians treating PCOS with obesity have limited data on combining semaglutide with metformin, and the trial targets metabolic profile and insulin resistance endpoints over 12 weeks.
03Only 30 patients were enrolled by convenience sampling in an open-label design at a single center, and results are not yet posted.

From the source

Semaglutide in Women With Polycystic Ovary Syndrome and Obesity
NCT06896981 · PHASE2/PHASE3 · COMPLETED · Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · Conditions: Polycystic Ovary Syndrome (PCOS) Women, Obesity.

Read at clinicaltrials.gov

Source URL https://clinicaltrials.gov/study/NCT06896981