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Peptide.Wire

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Menopause hormone therapy linked to greater semaglutide weight loss in 3,900 women

Mayo Clinic Florida cohort found 11% weight loss at one year with hormone therapy plus semaglutide versus 9.5% with semaglutide alone.

MH
By Maren Holt · Senior Reporter, GLP-1
Oct 21 06:00 ETSource: Drugs.com

The wire

  1. 01Research set for presentation at the Menopause Society annual meeting followed about 2,400 women on semaglutide for roughly 26 months and 1,500 on tirzepatide for about 16 months.
  2. 02Clinicians prescribing incretins to postmenopausal patients may see differing response by hormone therapy status; 22% of combination users lost 20% or more body weight versus 18% on semaglutide alone.
  3. 03The effect was smaller with tirzepatide (6.6% versus 5.9% at three months), the work is an observational conference abstract, and lead author Regina Castaneda says more research is needed.

From the source

Menopause Hormone Therapy Might Boost GLP-1 Weight Loss Results, Study Says

WEDNESDAY, Oct. 21, 2026 — Hormone therapy for menopause might actually boost the weight-loss benefits of drugs like Ozempic and Zepbound, a new study says.Middle-aged women taking hormone therapy to manage hot flashes and other symptoms of...

Read at drugs.com
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