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Cardiovascular safety of orforglipron versus insulin glargine in adults with type 2 diabetes at increased cardiovascular risk (ACHIEVE-4): a phase 3, event-driven, randomised, open-label, non-inferiority, active comparator trial

Lancet (London, England) · 2026 Sep 30 · Klein KR, Wysham C, Tuttle KR et

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By Maren Holt · Senior Reporter, GLP-1
Sep 29 20:00 ETSource: Lancet (London, England)

From the source

Cardiovascular safety of orforglipron versus insulin glargine in adults with type 2 diabetes at increased cardiovascular risk (ACHIEVE-4): a phase 3, event-driven, randomised, open-label, non-inferiority, active comparator trial

Lancet (London, England) · 2026 Sep 30 · Klein KR, Wysham C, Tuttle KR et al.

Read at pubmed.ncbi.nlm.nih.gov
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