UC Santa Cruz team reports P3 peptide aggregates faster than amyloid beta
Researchers say the overlooked fragment forms its own amyloid deposits and may harm neurons, arguing both peptides should be studied together.
PR
By Priya Raman · Science Reporter
Oct 14 08:44 ETSource: NewsBytes
The wire
- 01Researchers at UC Santa Cruz report that the P3 peptide forms protein clumps faster than amyloid beta and may itself be harmful to neurons, forming distinct amyloid deposits.
- 02Decades of Alzheimer's drug development have targeted amyloid beta with limited success, so a second aggregating fragment could change how targets are chosen.
- 03The report is early laboratory work; the account gives no sample sizes, assay details or human evidence that P3 drives disease in patients.
From the source
Read at newsbytesapp.comUC Santa Cruz finds P3 peptide may reshape Alzheimer's research
Researchers at UC Santa Cruz have found a largely overlooked peptide, P3, that could be a big deal for understanding and treating Alzheimer's disease.
