Phage screening identifies tuberculosis peptides presented by HLA-E
The work points to candidate antigens for HLA-E-restricted T cell responses against Mycobacterium tuberculosis.
PR
By Priya Raman · Science Reporter
Oct 21 02:33 ETSource: Bioengineer.org
The wire
- 01Researchers used phage display screening to identify Mycobacterium tuberculosis-derived peptides that bind the non-classical MHC molecule HLA-E.
- 02HLA-E-restricted peptides are of interest for TB vaccine design, a different lane from the recovery and metabolic peptides most readers track.
- 03Details on validation, sample size and whether candidates were tested in human cells or animals are not available from the headline alone.
From the source
Read at bioengineer.orgPhage screening identifies candidate tuberculosis peptides for HLA-E
