Review frames MOTS-c as context-dependent signal with double-edged role in tumors
The mitochondrial-derived peptide is described as protective in metabolic homeostasis while its effects in cancer biology are presented as uncertain.
PR
By Priya Raman · Science Reporter
Oct 10 23:08 ETSource: Bioengineer.org
The wire
- 01A new review argues MOTS-c acts as a context-dependent stress signal, with protective roles in metabolic homeostasis but potentially double-edged effects in tumor biology.
- 02Readers tracking mitochondrial and longevity peptides get a framing that cautions against assuming uniformly beneficial effects of MOTS-c across tissues and disease states.
- 03This is a narrative review rather than new experimental or human data, and the summary available offers no specific studies, doses or endpoints.
From the source
Read at bioengineer.orgMOTS-c: The Tiny Mitochondrial Peptide That Behaves Differently in Health and Cancer
A new review argues that the mitochondrial peptide MOTS-c acts as a context-dependent stress signal with protective roles in metabolic homeostasis but potentially double-edged effects in tumor biology.
