GLP-1glp-1 receptor agonistscontraceptionreproductive healthajog

AJOG review flags knowledge gaps on GLP-1 agonists and hormonal contraception

Authors call for routine contraceptive counseling when starting GLP-1 receptor agonists in women of reproductive age.

By Maren Holt · Senior Reporter, GLP-1

Oct 7 20:00 ETSource: American journal of obstetrics and gynecology

The wire

01A narrative review in the American Journal of Obstetrics and Gynecology synthesizes the limited literature on pharmacokinetic and pharmacodynamic interactions between GLP-1 receptor agonists and hormonal contraception.
02Prescribers of semaglutide and tirzepatide in reproductive-age patients are urged to make contraceptive counseling a routine part of initiation.
03The review is narrative rather than systematic and the authors state that studies evaluating the two drug classes together are limited, leaving significant gaps unresolved.

From the source

Contraceptive use and GLP-1 receptor agonists: an intersection of metabolic and reproductive health
American journal of obstetrics and gynecology · 2026 Oct 8 · Yee HM, Han LL et al.

Read at pubmed.ncbi.nlm.nih.gov

Source URL https://pubmed.ncbi.nlm.nih.gov/42849807/