GLP-1glp-1 receptor agonistsbody contouringsurgical complicationsjpras

Danish cohort links GLP-1 exposure to infection after body contouring surgery

Among 282 patients, prior bariatric surgery showed no increased complication risk, while GLP-1 receptor agonist use did despite standardised preoperative optimisation.

By Maren Holt · Senior Reporter, GLP-1

Sep 23 20:00 ETSource: Journal of plastic, reconstructive & aesthetic surgery : JPRAS

The wire

01In a retrospective single-centre study of 282 adults operated on at Aalborg University Hospital between December 2022 and December 2025, preoperative GLP-1 receptor agonist exposure was associated with postoperative infection (OR 3.72, 95% CI 1.52-9.07) versus lifestyle weight loss.
02Wound dehiscence requiring intervention under general anaesthesia was also more likely (OR 16.71, 95% CI 1.99-139.88), a signal surgeons and prescribers may weigh when planning post-weight-loss procedures.
03The study is retrospective and single-centre, the dehiscence confidence interval is extremely wide, and no association was found for local-anaesthesia dehiscence or postoperative bleeding.

From the source

GLP-1 receptor agonist use and postoperative complications after body contouring surgery following massive weight loss
Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 2026 Sep 24 · Djebbara-Bozo N, Yilmaz M, Saritas S et al.

Read at pubmed.ncbi.nlm.nih.gov

Source URL https://pubmed.ncbi.nlm.nih.gov/42874170/