Boston Children's lab reports peptide cuts neuropathic pain in mice

The wire

1. 01Researchers in Clifford Woolf's lab at Boston Children's Hospital's FM Kirby Neurobiology Center describe a peptide that reduces chronic neuropathic pain by disrupting interactions within nociceptors.
2. 02Non-opioid approaches to neuropathic pain remain scarce, so an intracellular peptide strategy is of interest to clinicians tracking the analgesic pipeline.
3. 03This is a mouse study; no human dosing, delivery route or safety data are reported, and translation to patients is unestablished.

From the source

Novel peptide approach reduces chronic neuropathic pain in mice

Understanding and treating chronic neuropathic pain has remained challenging due to its complex nature. New research from the lab of Clifford Woolf, MB, BCh, PhD, at Boston Children's Hospital's FM Kirby Neurobiology Center describes a novel approach for reducing pain by disrupting interactions within pain-sensing nerve cells called nociceptors