Graphene oxide nanosheets deliver neuropeptide Y into rat amygdala

The wire

1. 01Scientists used graphene oxide nanosheets to carry neuropeptide Y into the amygdala of rats, selectively erasing fear memories via Y1 receptor-expressing circuits.
2. 02The work is an early signal for targeted peptide delivery into the brain, a persistent obstacle for neuropeptide therapeutics.
3. 03This is a rodent study with no human data; the nanomaterial carrier itself would need separate safety work before any clinical translation.

From the source

Graphene Oxide Nanosheets Deliver Neuropeptide Y to Erase Fear Memories in Rats

Scientists have used graphene oxide nanosheets to deliver neuropeptide Y into the rat amygdala, selectively erasing fear memories through Y1 receptor-expressing circuits while leaving anxiety behaviors intact.