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GLP-1retatrutidetriumph-2lancettype 2 diabetes

Lancet commentary weighs retatrutide results from TRIUMPH-2 in type 2 diabetes

Holst and colleagues review what the obesity and type 2 diabetes trial of the triple agonist adds to the incretin evidence base.

MH
By Maren Holt · Senior Reporter, GLP-1
Oct 9 07:00 ETSource: Lancet (London, England)

The wire

  1. 01The Lancet published a commentary by Holst and colleagues assessing findings from TRIUMPH-2, which tested retatrutide in adults with obesity and type 2 diabetes.
  2. 02Retatrutide is Eli Lilly's investigational triple agonist, and clinicians following the incretin pipeline track how it compares with existing GLP-1 and dual agonist options.
  3. 03The piece is editorial commentary rather than new trial data, and the drug remains investigational pending full phase 3 reporting and regulatory review.

From the source

Retatrutide in adults with obesity and type 2 diabetes: what have we learned from TRIUMPH-2?

Lancet (London, England) · 2026 Oct 10 · Holst JJ et al.

Read at pubmed.ncbi.nlm.nih.gov
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