Elamipretide restores fertility in aged mice after seven-day course
Researchers attribute the recovery in oocyte quality and embryo development to a vitamin B6–VEGF pathway, with preliminary signals reported in human eggs.
PR
By Priya Raman · Science Reporter
Oct 5 13:26 ETSource: Bioengineer.org
The wire
- 01A seven-day course of the mitochondria-targeting peptide elamipretide (SS-31) restored oocyte quality, embryo development and fertility in aged mice, acting through a vitamin B6–VEGF pathway.
- 02Elamipretide is already tracked by longevity-focused clinicians and researchers; this extends its reported mitochondrial effects into reproductive aging.
- 03The core result is an animal study, and the human egg findings are described only as preliminary, with no clinical trial data in reproductive medicine.
From the source
Read at bioengineer.orgMitochondria-Targeting Peptide Elamipretide Rejuvenates Aging Eggs and Restores Fertility in Mice
A seven-day course of the mitochondria-targeting peptide elamipretide restored oocyte quality, embryo development and fertility in aged mice by acting through a vitamin B6–VEGF pathway, with encouraging preliminary results in human eggs.
