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Researchmyokineace2fatty liverpreclinical

Exercise-linked muscle peptide cuts fatty liver via ACE2 in mice

Researchers report the myokine acts through the ACE2 pathway, linking exercise signaling to hepatic fat reduction in an animal model.

PR
By Priya Raman · Science Reporter
Oct 22 00:13 ETSource: Bioengineer.org

The wire

  1. 01The reported work describes an exercise-induced muscle-derived peptide reducing fatty liver in mice, with ACE2 identified as the mediating pathway.
  2. 02Exercise-mimetic peptides are an area readers watch for metabolic indications, and a defined receptor pathway gives a target for any future therapeutic candidate.
  3. 03Findings are in mice only; no human dosing, safety or efficacy data are reported and translation to clinical use is unestablished.

From the source

Exercise-linked muscle peptide reduces fatty liver through ACE2 in mice

Read at bioengineer.org
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