Semaglutide program lifts gait speed in 22 Japanese obesity patients

The wire

1. 01A retrospective study in Internal Medicine followed 22 adults with obesity and musculoskeletal disorders through a 12-month program of semaglutide, bimonthly nutrition counseling and physical therapist-guided exercise; weight fell from 89.2 kg to 81.5 kg.
2. 02Gait speed improved significantly (p<0.001) and pain scores improved, suggesting clinicians could track mobility recovery alongside weight when assessing obesity treatment.
3. 03Gains in gait speed did not correlate with weight loss (r=0.22) or pain reduction (r=-0.04); the sample was 22 patients, retrospective, uncontrolled and bundled with exercise and diet intervention.

From the source

Changes in Gait Speed During a 12-Month Multidisciplinary Obesity Management Program Including Semaglutide: A Real-World Observational Study in Japanese Adults With Musculoskeletal Disorders

Internal medicine (Tokyo, Japan) · 2026 Oct 15 · Tomita M, Harashima F, Takeda N et al.