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Researchers develop ELISA detecting CJC-1295 in horse plasma at 12.5 pg/mL

The assay uses monoclonal antibodies against the peptide and was validated in thoroughbreds given 10mg subcutaneously, treating the DAC conjugate as a protein doping agent.

PR
By Priya Raman · Science Reporter
Oct 13 20:00 ETSource: Drug testing and analysis

The wire

  1. 01Writing in Drug Testing and Analysis, Timms and colleagues report an ELISA detecting CJC-1295 protein conjugates in equine plasma down to 12.5 pg/mL.
  2. 02CJC-1295's drug affinity complex crosslinks the peptide to plasma proteins with free cysteine residues, extending half-life and making it behave more like a protein doping agent than a typical peptide.
  3. 03Validation used blood from thoroughbred racehorses after a single 10mg subcutaneous dose; the paper does not address human testing applications.

From the source

Detection of CJC-1295 in Equine Plasma by ELISA

Drug testing and analysis · 2026 Oct 14 · Timms M, Cawley A, Steel R et al.

Read at pubmed.ncbi.nlm.nih.gov
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