Researchers develop ELISA detecting CJC-1295 in horse plasma at 12.5 pg/mL
The assay uses monoclonal antibodies against the peptide and was validated in thoroughbreds given 10mg subcutaneously, treating the DAC conjugate as a protein doping agent.
PR
By Priya Raman · Science Reporter
Oct 13 20:00 ETSource: Drug testing and analysis
The wire
- 01Writing in Drug Testing and Analysis, Timms and colleagues report an ELISA detecting CJC-1295 protein conjugates in equine plasma down to 12.5 pg/mL.
- 02CJC-1295's drug affinity complex crosslinks the peptide to plasma proteins with free cysteine residues, extending half-life and making it behave more like a protein doping agent than a typical peptide.
- 03Validation used blood from thoroughbred racehorses after a single 10mg subcutaneous dose; the paper does not address human testing applications.
From the source
Read at pubmed.ncbi.nlm.nih.govDetection of CJC-1295 in Equine Plasma by ELISA
Drug testing and analysis · 2026 Oct 14 · Timms M, Cawley A, Steel R et al.
Source URL https://pubmed.ncbi.nlm.nih.gov/42876013/
