Systematic review finds GLP-1 agonists cut HbA1c in steroid-induced dysglycaemia

The wire

1. 01A PRISMA systematic review of 13 studies, mostly retrospective cohorts and largely in solid organ transplant recipients with post-transplant diabetes, linked GLP-1 receptor agonists to lower HbA1c, weight and insulin dose.
2. 02Clinicians managing steroid-induced hyperglycaemia or post-transplant diabetes currently default to insulin; the review suggests GLP-1 agonists reduced injection burden with a low rate of hypoglycaemia.
3. 03No outcome was informed by more than three studies and certainty was very low, so pooled estimates are exploratory; the authors call for prospective trials characterising glucocorticoid exposure.

From the source

GLP-1 Receptor Agonist Therapy for Glucocorticoid-Induced Dysglycaemia: A Systematic Review

Diabetes, obesity & metabolism · 2026 Oct 8 · Jędrasek A, Ulicka W, Lisowska K et al.