GLP-1semaglutidebariatric surgeryobesitysurgical endoscopy

Semaglutide after sleeve gastrectomy improves 24-month weight loss in 88-patient review

Patients started on semaglutide six months post-surgery for suboptimal loss had lower BMI and better lipids than surgery-only controls at 12 and 24 months.

By Maren Holt · Senior Reporter, GLP-1

Oct 7 20:00 ETSource: Surgical endoscopy

The wire

01Retrospective single-center study of 88 laparoscopic sleeve gastrectomy patients; 43 received adjunctive semaglutide from month six for plateaued weight loss, 45 had standard follow-up.
02Groups were comparable at six months, but the semaglutide arm showed greater percentage total and excess weight loss plus higher HDL and lower triglycerides at 24 months.
03Authors call the work preliminary; it is retrospective, single-center, non-randomized, and doses and adherence details are not reported in the abstract.

From the source

The impact of semaglutide initiated six months after laparoscopic sleeve gastrectomy on long-term weight loss and metabolic outcomes: single-center preliminary study
Surgical endoscopy · 2026 Oct 8 · Jeske P, Roleder J, Zastawna K et al.

Read at pubmed.ncbi.nlm.nih.gov

Source URL https://pubmed.ncbi.nlm.nih.gov/42850299/